I cannot reproduce this every time, but if I open my solution and quickly right-click on a project and select "Run Unit tests" an information dialog comes up: "Selected items do not contain any tests". In fact, the project does contain unit tests and I can run them if I wait a little. I'm guessing that ReSharper simply hasn't read the project yet and hasn't found the unit tests. The error is misleading to the user, so it should either: 1) Wait for initialisation to complete if the "Run Unit Tests" command is executed; or 2) Disable the command until initialised; or at the very least 3) Give a more appropriate message.